Transferrin, HRP, Invitrogen™

Descrizione

Concentration may vary slightly from lot-to-lot, see lot-specific datasheet for exact concentration. Product Purity: The precipitin line(s) against goat anti-mouse whole serum is (are) the same as that (those) against goat anti-mouse transferrin when assayed by immunoelectrophoresis at an antigen concentration of 20 mg/mL. Transferrin Concentration: 1.0 mg/mL after reconstitution. Restoration and Storage: Store product at 4°C until opened. Restore with 1.1 mL distilled water. Centrifuge product if it is not completely clear after standing for 1-2 hours at room temperature. (To judge clarity, draw product into a clean pasteur pipette). Product is stable for several weeks at 4°C as an undiluted liquid. After dilution, do not use for more than one day. To extend the shelf-life of this product, add an equal volume of glycerol to make a final concentration of 50% glycerol and store at -20°C. Country of Origin: USA

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.