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PTPN11 Mouse anti-Human, Mouse, Rat, Clone: 3F8A8, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 66795-1-IG-150UL
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Descrizione
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.Specifica
| PTPN11 | |
| Monoclonal | |
| 0.8 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P35235, P41499, Q06124 | |
| PTPN11 | |
| PTPN11 Fusion Protein Ag13649 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 3F8A8 | |
| Unconjugated | |
| PTPN11 | |
| BPTP3, CFC, NS1, PTP 1D, PTP 2C, PTP2C, PTPN11, SH PTP2, SH PTP3, SHP 2, SHP2, SHPTP2 | |
| Mouse | |
| Protein G | |
| RUO | |
| 19247, 25622, 5781 | |
| -20°C | |
| Liquid |
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