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PTEN/MMAC1 Ab-4 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ PTEN/MMAC1 Ab-4, Mouse Monoclonal Antibody.
210.12€ - 979.20€
Specifica
| Antigene | PTEN/MMAC1 Ab-4 |
|---|---|
| Clone | 17.A |
| Applicazioni | Immunohistochemistry (Paraffin) |
| Classificazione | Monoclonal |
| Coniugato | Unconjugated |
Descrizione
PTEN/MMAC1, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling.Host Species: Mouse
Clone: 17.A
Isotype: IgM/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human PTEN protein
Molecular Weight: 60kDa
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry
Note:
USA: RUO; Int'l: RUO
Specifica
| PTEN/MMAC1 Ab-4 | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Mouse | |
| Cancer and Tumor Biology | |
| Recombinant human PTEN protein | |
| Primary |
| 17.A | |
| Monoclonal | |
| Concentrated | |
| RUO | |
| Human | |
| IgM κ |
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