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Nalidixic acid, 99.5%, Thermo Scientific Chemicals

Nalixidic acid, or nalixidin, CAS # 389-08-2, is a quinolone antibiotic used to inhibit DNA gyrase and prevent cell division.

39.41€ - 321.92€

Chemical Identifiers

CAS 389-08-2
Molecular Formula C12H12N2O3
Molecular Weight (g/mol) 232.24
MDL Number MFCD00006884
InChI Key MHWLWQUZZRMNGJ-UHFFFAOYSA-N
Synonym nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
PubChem CID 4421
ChEBI CHEBI:100147
IUPAC Name 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
SMILES CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
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10373622
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Thermo Scientific Acros
169900050 		5 g Glass bottle
39.41€
5g
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10711831
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Thermo Scientific Acros
169900250 		25 g Glass bottle
123.19€
25g
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10391564
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Thermo Scientific Acros
169901000 		100 g Glass bottle
321.92€
100g
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Nalixidic acid is a synthetic quinolone that is a monocarboxylic acid composed of 1,8-naphthyridine substituted with carboxylic acid, ethyl, and methyl groups

• Nalixidic acid is a DNA gyrase inhibitor that prevents DNA synthesis and subsequent cell divisions

Applications

• Nalixidic acid is primarily effective against gram-negative bacteria

• It may be useful for bacterial resistance studies and laboratory research on drug allergies and cross-reactivity

• Nalixidic acid is suitable for high-performance liquid chromatography (HPLC) and related biochemistry laboratory applications

Specifications

Chemical Identifiers

389-08-2
232.24
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
4421
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
C12H12N2O3
MFCD00006884
nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
CHEBI:100147
CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O

Specifications

389-08-2
100.0
White to Yellow
99.5%
MFCD00006884
15, 6444
Solubility in water: 0.1g/L (23°C). Other solubilities: soluble in alkali solutions,35mg/mL chloroform- 1.6mg/mL toluene (23°C),1.3mg/mL methanol- 0.9mg/mL ethanol (23°C),0.1mg/mL ether (23°C)
CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
232.24
CHEBI:100147
99.5%
Nalidixic acid, 99.5%
99.4
225.0°C to 231.0°C
Authentic
C12H12N2O3
25, V,7, 384
nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
4421
232.24
Powder
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Safety and Handling

Safety and Handling

GHS H Statement
May cause an allergic skin reaction.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.

GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
Wear eye protection/face protection.

GHS Signal Word: Danger

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Product Identifier
  • Nalidixic acid

Signal Word
  • Danger

Hazard Category
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1

Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

SDS
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Product Certifications

RUO – Research Use Only

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