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KRAS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifica

Antigene KRAS
Concentrazione 0.26 mg/mL
Applicazioni Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry, Flow Cytometry
Classificazione Polyclonal
Coniugato Unconjugated
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
16859553
Vedere i documenti
Proteintech
12063-1-AP-20UL
20 μL
145.00€
20µL
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16849553
Vedere i documenti
Proteintech
12063-1-AP-150UL
150 μL
410.00€
150µL
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Descrizione

Descrizione

This KRAS antibody (12063-1-AP) has weaker cross reaction to HRAS and NRAS.

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
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KRAS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

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