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Invitrogen™ Human IL-23 R ELISA Kit
ELISA
Specifica
| Numero di accesso | IBD17; IL 23 R; IL-23 receptor; Il23r; IL-23 R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor |
|---|---|
| Intervallo saggio | 0.2 to 50 ng/mL |
| Assay Sensitivity | 0.2 ng/mL |
| Coniugato | HRP |
| Product Type | ELISA |
Descrizione
Human IL-23 R quantitates human IL-23 R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-23 R.
IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.Specifica
| IBD17; IL 23 R; IL-23 receptor; Il23r; IL-23 R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor | |
| 0.2 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| Il23r | |
| <10 | |
| HRP | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| IL23R | |
| 4 hrs 45 mins |
| 0.2 to 50 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 149233 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
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