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Tocris Bioscience™ ERK5-IN-1

Potent and selective ERK5 inhibitor

317.00 € - 1255.00 €

Specifications

Purity >98%
Description ERK5-IN-1
Molecular Weight (g/mol) 638.8
Product Type ERK5-IN-1
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18747068
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Tocris Bioscience™
5393/10
10 mg This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A
18732988
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Tocris Bioscience™
5393/50
50 mg This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A
Description

Description

Potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.
Specifications

Specifications

>98%
ERK5-IN-1
638.8
ERK5-IN-1
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For Research Use Only

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