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Tocris Bioscience™ ERK5-IN-1
Potent and selective ERK5 inhibitor
317.00 € - 1255.00 €
Specifications
Purity | >98% |
---|---|
Description | ERK5-IN-1 |
Molecular Weight (g/mol) | 638.8 |
Product Type | ERK5-IN-1 |
Description
Potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.Specifications
>98% | |
ERK5-IN-1 | |
638.8 | |
ERK5-IN-1 |
For Research Use Only
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