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  6. Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Deoxycholic acid, sodium salt, CAS # 302-95-4, also designed as sodium deoxycholate, is a biological anionic bile acid detergent that is especially useful for disrupting and dissociating protein interactions.

47.34€ - 315.57€

Identificatori chimici

CAS 302-95-4
Formula molecolare C24H39NaO4
Molecular Weight (g/mol) 414.56
Numero MDL MFCD00064139
InChI Key FHHPUSMSKHSNKW-SMOYURAASA-M
Sinonimo sodium deoxycholate
PubChem CID 91810855
SMILES [Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
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Prodotti 3
Codice del prodotto Marca Quantità Imballaggio Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Imballaggio Prezzo Quantità e disponibilità  
10104560
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Thermo Scientific Acros
218590250 		25 g Bottiglia in vetro
47.34€
25g
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10732451
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Thermo Scientific Acros
218591000 		100 g Bottiglia in vetro
97.18€
100g
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10562904
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Thermo Scientific Acros
218595000 		500 g Bottiglia in vetro
315.57€
500g
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Descrizione

Descrizione

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
  • The compound is an intermediate in the production of corticosteroids
  • In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling


Applications

  • Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
  • It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
  • It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
  • Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
Specifica

Identificatori chimici

302-95-4
414.56
FHHPUSMSKHSNKW-SMOYURAASA-M
91810855
C24H39NaO4
MFCD00064139
sodium deoxycholate
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Specifica

Deoxycholic acid, sodium salt
White to Cream
5% max. (2 g, 105°C, 4 hrs)
99%
MFCD00064139
14, 2899
sodium deoxycholate
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
414.56
414.58
Ultrapuro
302-95-4
7.5 to 10 (5% aq. soln.)
Authentic
C24H39NaO4
10, III, 1642
+42° to +46° (20°C, 589nm) (c=2, water)
FHHPUSMSKHSNKW-SMOYURAASA-M
sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
91810855
98.5 to 102% (on dry substance)
Crystalline Powder
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Sicurezza e movimentazione

Sicurezza e movimentazione

GHS H Statement:
Harmful if swallowed.
May cause respiratory irritation.

GHS P Statement:
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

Identificativo prodotto
  • Deoxycholic acid, sodium salt

Avvertenza
  • Attenzione

Categoria di pericolo
  • Tossicità acuta Categoria 4
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3

Indicazioni di pericolo
  • H335-Può irritare le vie respiratorie.
  • H302-Nocivo se ingerito.

Consigli di prudenza
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P264-Lavare accuratamente dopo l'uso.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.

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RUO – Research Use Only

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