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Chromomycin A3, 97%

Codice prodotto. 15415229
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Quantità:
10 mg
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

CAS: 7059-24-7 | C57H82O26 | 1183.257 g/mol

Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate G-C box, induced by oxidative stress or DNA damage. Furthermore, by inhibiting transcription, Chromomycin A3 and its structural analogs can inhibit protein biosynthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate ″G-C&Pr
TRUSTED_SUSTAINABILITY

Specifica

Materiale o nome chimico Chromomycin A3
Tipo Chromomycin A3
Forma fisica Powder
CAS 7059-24-7
Punto di fusione 185°C (decomposition)
Colore Yellow
Quantità 10 mg
Formula molecolare C57H82O26
Numero MDL MFCD00043151
Numero UN UN3462
Indice di Merck 14,2238
Informazioni di solubilità Soluble in ethanol,DMSO,and ethyl acetate (10mg/ml).
InChI Key ZYVSOIYQKUDENJ-YVQLHGKOSA-N
SMILES CC1C(C(CC(O1)OC2C(CC3=C(C2=O)C(=C4C(=C3)C=C(C(=C4O)C)OC5CC(C(C(O5)C)OC(=O)C)OC6CC(C(C(O6)C)OC)O)O)C(C(=O)C(C(C)O)O)OC)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC(=O)C)(C)O)O
IUPAC Name [(2R,3R,4R,6S)-6-[[(6S,7S)-6-[(2S,4R,5R,6R)-4-[(4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-7-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-4,10-dihydroxy-3-
Molecular Weight (g/mol) 1183.257
PubChem CID 23928042
Peso formulazione 1183.3
Percent Purity 97%
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