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Invitrogen™ OX40 Monoclonal Antibody (443318), PE
Rat Monoclonal Antibody
Marca: Invitrogen™ MA523676
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Descrizione
In Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed.
OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.
Specifica
OX40 | |
Monoclonal | |
PE | |
Tnfrsf4 | |
ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; Tnfrsf4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; Txgp1l | |
Rat | |
Protein A/G | |
RUO | |
7293 | |
4°C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
443318 | |
Buffered saline solution with BSA and 0.09% sodium azide | |
P43489 | |
Tnfrsf4 | |
Mouse myeloma cell line NS0-derived recombinant human OX40/TNFRSF4 Leu29-Ala216. | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG2a |
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